General academic work

Influential research outputs

The Lancet

Our research helped change India’s cataract surgery policy

Mobile camps provided cataract surgery to people in rural areas. Amarjit’s research showed one-third of patients were blind in the operated eye 12 months after the operation. This contributed to India’s shift to a fixed-facility approach.

Cost-effectiveness of public-funded options for cataract surgery in Mysore, India

Singh A, Garner P, Floyd K

Lancet 2000; 355: 180-184

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BMJ

Our research changed diarrhoea treatment worldwide

Oral rehydration salt solution helps save many lives from diarrhoea in some countries. We synthesised existing trials and showed a newer, less-salty formula was more effective. The World Health Organization changed their global formula within a year.

Reduced osmolarity oral rehydration solution for treating dehydration due to diarrhoea in children: systematic review

Hahn S, Kim Y, Garner P.

BMJ 2001;323:81

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The Lancet

Our synthesis led to a major shift in malaria treatment worldwide

Artemisinin antimalarials appeared as other drugs were failing. We analysed artemisinin combination treatments with all the trialists involved. The World Health Organization then recommended these formulations worldwide.

Artesunate combinations for treating uncomplicated malaria: A prospective individual patient data meta-analysis

International Artemisinin Study Group

Lancet 2004;363:9-17

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WHO

Our reviews were used for most new WHO malaria drug treatment recommendations over 15 years

I was the guideline methodologist and head of the systematic review team for the WHO Malaria Chemotherapy Guidelines 2004 to 2018 (1st Ed. 2006; 2nd Ed.2010; 3rd Ed. 2015). Fourteen of our reviews were used in the 3rd edition (8 led by LMIC authors).

Guidelines for the treatment of malaria. Third edition

Malaria Chemotherapy Guidelines Development Group

Geneva: World Health Organization; 2015

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Cochrane

Our research challenged WHO directly observed therapy dogma for people with tuberculosis

In 2002, WHO made a global recommendation that all TB patients should be watched taking their medication. In a series of reviews, we concluded there was no strong evidence that this policy was beneficial. The review was controversial as it challenged WHO dogma. Over time, the review helped the WHO nuance its claims, messaging, and recommendations.

Directly observed therapy for treating tuberculosis

Karumbi J, Garner P

Cochrane Database of Systematic Reviews. 2015(5)

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BMJ

We developed global updating guidelines for systematic reviews

I coordinated the development of guidance about when to prepare new editions of systematic reviews. This consensus guidance was built on our experience across Cochrane review groups.

When and how to update systematic reviews: consensus and checklist

Garner P, Hopewell S, Chandler J, Maclehose H, Schünemann HJ, Akl EA, et al.

BMJ. 2016:i3507

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Indian Journal of Medical Research

Contribution to India guidelines for extrapulmonary tuberculosis

Management of people suspected of extrapulmonary tuberculosis in India is varied. We were invited by the Government of India and the All India Institute of Medical Sciences to serve as methodologists to help build national guidelines.

Index-TB Guidelines: Guidelines on extrapulmonary tuberculosis for India

Sharma SK, Ryan H, Khaparde S, Sachdeva KS, Singh AD, Mohan A, et al.

Indian J Med Res. 2017;145(4):448–63

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Cochrane

Our research, spanning 20 years, challenged global dogma that mass treatment for intestinal helminths led to increased wealth and health of whole continents

The WHO and NGO’s launched campaigns to “deworm the world” of intestinal helminths in children in poor countries to improve their health, development and wealth. The review was controversial as it challenged one of the most celebrated interventions in development economics. With six subsequent editions, contemporary evidence of little or no effect became more obvious.

Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas

Taylor‐Robinson DC, Maayan N, Donegan S, Chaplin M, Garner P

Cochrane Database of Systematic Reviews. 2019(9)

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PLoS Biology

Contributed to guidelines for reporting animal research studies

I was the methodologist on the Guidelines Panel for a new edition of the Reporting Animal Research Studies Guidelines (ARRIVE II). This has been cited over 11,000 times.

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen O, Rawle F, Peynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Wurbel H

PLoS Biol. DOI: 10.1371/journal.pbio.3000410

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General research since 2020

Excluding Covid-19 and fatigue conditions

PLoS One

Testing for saturation in qualitative evidence syntheses: An update of HIV adherence in Africa

Rohwer A, Hendricks L, Oliver S, Garner P.

PLoS One. 2021;16(10):e0258352

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American Journal of Public Health

Enhancing Public Health Systematic Reviews With Diagram Visualization

Rohwer A, Taylor M, Ryan R, Garner P, Oliver S

Am J Public Health. 2021;111(6):1029–34

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PLoS One

Suicide rates and suicidal behaviour in displaced people: A systematic review

Cogo E, Murray M, Villanueva G, Hamel C, Garner P, Senior SL, et al.

PLoS One. 2022 Mar 10;17(3):e0263797

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Research Synthesis Methods

Identifying and managing problematic trials: A research integrity assessment tool for randomized controlled trials in evidence synthesis

Weibel S, Popp M, Reis S, Skoetz N, Garner P, Sydenham E

Res Synth Methods. 2023 May;14(3):357-369

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Clinical Epidemiology and Global Health

The India brain infections guidelines project: Global evidence for local application

Rupali P, Singh B, Gracelin Princy N, Sara John J, Kuehn R, Solomon T, et al.

Clinical Epidemiology and Global Health, 2024; 27

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Health Research Policy and Systems

Use of qualitative research in World Health Organisation guidelines: a document analysis

Taylor M, Garner P, Oliver S, Desmond N

Health Res Policy Syst. 2024;22(1):44

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Cochrane

Systematic reviews of clinical laboratory studies: Pilot risk of bias tool developed by consensus

Fox T, Hunt BJ, Ariens RAS, Towers GJ, Lever R, Garner P, et al.

Cochrane Evid Synth Methods. 2024 Aug 12;2(8):e12098

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Health Policy and Planning

Expert stakeholders on the role of qualitative research in World Health Organisation guidelines

Taylor M, Garner P, Oliver S, Desmond N

Health Policy Plan. 2026 Mar 10;41(3):433-441

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Bulletin World Health Organization

National guideline development and adaptation, Egypt

Kheirandish M, Tamim MA, Rashidian A, El-Asady R, Al Qasseer N, Gad El-Kareem G, et al.

Bull World Health Organ. 2026 May 1;104(5):350-356

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Academic work in Covid-19 and fatigue conditions

Since 2023,I have developed a research portfolio related to a whole-person approach to health care, which views illness and symptoms as part of biology, with persistent physical symptoms just being a condition like any other — with biological, psychological and social components, all of which are important in understanding the conditions and the different strategies to recover.

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Paul has more than 500 research publications.

The full list can be viewed here:

View Paul’s ORCID profile →